STUTTGART, Germany I March 17, 2017 I Sales of branded originator biologics in 2016 continued to reach a record high of US$ 163 bln, a plus of 5.8% compared with the previous year. Growth drivers were therapeutic antibodies fortreatment of cancer and inflammatory diseases, especially the emerging immuno-oncology antibodies and novel anti-inflammatory antibodies different from anti-TNF. Interestingly, sales of all anti-inflammatory antibodies including the anti-TNF family were 63% higher than those of the cancer antibodies. Nearly two-thirds of all biologics sales are attributable to antibodies, while 2016 sales of therapeutic proteins were 10% lower than those in 2015. Nearly all classes of therapeutic proteins except enzyme replacement therapies have seen a declineof sales in 2016.