GM-CSF Targeted Therapies

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Publisher: La Merie Publishing
Format: Word Table
Product Line: Target Pipeline List
Product Code: LMTPL042
Release Date: April of 2019
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GM-CSF Targeted Therapies – Target Pipeline List 04/2019

Targets: GM-CSF; granulocyte macrophage-colony stimulating factor; GM-CSF receptor; GM-CSF-R

This Target Pipeline List provides an overview of therapeutic antibodies against GM-CSF or its receptor in development for treatment of inflammatory diseases.

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a type of protein that plays a central role in a broad range of immune mediated diseases, including rheumatoid arthritis.  It activates cells, including macrophages, leading to inflammation and joint damage. Neutralising the biological function of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor is a promising novel pharmacologic strategy for treatment of inflammatory diseases.

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