BARCELONA, Spain I May 20, 2022 I La Merie Publishing released today its newest report entitled “Cadherin 17: A target opportunity to develop effector-enhanced drug modalities”. This report describes and analyzes cadherin 17 as a target opportunity for development of effector-enhanced drug modalities as of May 2022. Cadherins are a...
Targeted Protein Degradation (TPD) by proteasomal PROTACs & molecular glues, lysosomal LYTACs and autophagic AUTOTACs or ATTECs provides plenty of opportunities to drug undruggable targets
BARCELONA, Spain I March 07, 2022 I La Merie Publishing released today its newest report entitled “Targeted Protein Degradation by Proteasomal, Lysosomal & Autophagy Pathways 2022: an industry landscape analysis of stakeholders, technologies, pipeline, partnering and financing”. This report describes and analyzes the field of Targeted Protein Degradation (TPD) from...
Prodrug antibodies and cytokines generated by masking technologies provide plenty of opportunities for founders, investors and partnerships
BARCELONA, Spain I October 06, 2021 I La Merie Publishing announced the release of its newest report about antibody and cytokine prodrugs . The report “Masked Antibodies & Cytokines As Prodrugs: a landscape analysis of stakeholders, technologies, pipelines, business and financing from an industry perspective” provides a landscape description and...
Vectorized Antibodies for In Vivo Expression by DNA and mRNA: an emerging new technology
BARCELONA, Spain I July 1, 2021 I La Merie Publishing announced the release of its newest report about in vivo delivery of nucleic acid-encoded antibodies . The report “Vectorized Antibodies for In Vivo Expression by DNA and mRNA: a landscape analysis of stakeholders, technologies, targets, business and financing from an...
Landscape Analysis of Targeted Protein Degradation by Novel PROTACs and Molecular Glues
BARCELONA, Spain I May 14, 2020 I La Merie Publishing announced the release of its newest report about Targeted Protein Degradation. The report “Targeted Protein Degradation by Novel PROTACs and Molecular Glues 2020: a landscape analysis of companies, technologies, targets, investors and partners from an industry perspective” provides a landscape...
The growing field of bispecific T-cell and NK cell engaging antibodies offers great opportunities for technology and product development companies
June 11, 2019 I We just released a new report describing and analyzing the field of bispecific antibodies used to redirect T-cells or natural killer (NK) cells to tumor cells. Since our first report about this subject three years ago, this specific field of biopharmaceutical research has grown enormously as...
Biologics sales reach another all time high in 2018 driven by innovative antibodies
April 4, 2018 I We just concluded our annual compilation and analysis of sales of recombinant therapeutic antibodies and proteins for the year 2018. The results show another all time high of global sales of more than US$ 202 mln, a plus of 7.3% compared with the previous year. The...
Analysis and ranking of TOP 25 pharma-based healthcare groups by business segment for revenues, sales, R&D costs and income
January 16, 2019 I We just released a management report for free download (see our menu „FREE reports“) in which we analyzed key financial data from the TOP 25 pharma-based health care companies with revenues of more than US$ 10 bln in the fiscal year 2017. The report entitled „TOP...
How many PD-1 and PD-L1 checkpoint inhibitors do we need?
STUTTGART, Germany I June 19, 2018 I La Merie Publishing released the results of an independent search for and evaluation of PD-1 and PD-L1 immune checkpoint inhibitors in preclinical and clinical development by pharmaceutical companies. This Competitive Intelligence report analyzes the competitive field of PD-1 and PD-L1 Immune Checkpoint Inhibitors...
Druggability of intracellular targets: a challenging, but highly rewarded goal for emerging technologies to generate TCR fusion proteins, TCRL antibodies and cell-permeating biologics
STUTTGART, Germany I January 25, 2018 I A tissue-based map of the human proteome suggests that about 75 % are intracellular or secreted targets not accessible for conventional monoclonal antibody and chimeric antigen receptor (CAR) T-cell therapy (Uhlen et al., Science, 2015). Thus, the large pool of intracellular protein targets,...