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La Merie Publishing is an independent business information provider for the biotechnology and pharmaceutical industry. We publish proprietary reports and prepare custom reports.

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Posted January 16, 2019

Analysis and ranking of TOP 25 pharma-based healthcare groups by business segment for revenues, sales, R&D costs and income

January 16, 2019 I We just released a management report for free download (see our menu „FREE reports“) in which we analyzed key financial data from the TOP 25 pharma-based health care companies with revenues of more than US$ 10

Posted June 19, 2018

How many PD-1 and PD-L1 checkpoint inhibitors do we need?

STUTTGART, Germany I June 19, 2018 I La Merie Publishing released the results of an independent search for and evaluation of PD-1 and PD-L1 immune checkpoint inhibitors in preclinical and clinical development by pharmaceutical companies. This Competitive Intelligence report analyzes

Posted May 23, 2018

TCR Engineered T-Cells are coming out of the shadows and into the light

The next two years will give definitive clues about the prospects of this promising treatment modality for solid tumors STUTTGART, Germany I May 23, 2018 I T-Cell Receptors (TCR) and Chimeric Antigen Receptors (CAR) are the cuttingedge of adoptive T-cell

Posted March 12, 2018

All time high of biologics sales in 2017 driven by cancer and innovative anti-inflammatory antibodies

STUTTGART, Germany I March 12, 2018 I Global sales of branded recombinant therapeutic antibodies and proteins in the calendar year 2017 reached an all time high of more than US$ 188 bln, as reported by La Merie Publishing. The increase

Posted January 25, 2018

Druggability of intracellular targets: a challenging, but highly rewarded goal for emerging technologies to generate TCR fusion proteins, TCRL antibodies and cell-permeating biologics

STUTTGART, Germany I January 25, 2018 I A tissue-based map of the human proteome suggests that about 75 % are intracellular or secreted targets not accessible for conventional monoclonal antibody and chimeric antigen receptor (CAR) T-cell therapy (Uhlen et al.,

Posted January 25, 2018

Druggability of intracellular targets: a challenging, but highly rewarded goal for emerging technologies to generate TCR fusion proteins, TCRL antibodies and cell-penetrating biologics

STUTTGART, Germany I January 25, 2018 I A tissue-based map of the human proteome suggests that about 75 % are intracellular or secreted targets not accessible for conventional monoclonal antibody and chimeric antigen receptor (CAR) T-cell therapy (Uhlen et al.,

Posted June 23, 2017

mRNA Vaccines & Therapeutics: are you ready to be on the ground floor of the next big new therapeutic modality?

STUTTGART, Germany I June 23, 2017 I Overlooked for many years, RNA languished as the ugly stepchild of nucleic acid vaccine development and was thought to be a poor choice for a therapeutic agent given its short half-life in vivo

Posted March 17, 2017

2016 was another record year of biologics sales with therapeutic antibodies accounting for two-thirds of total biologics sales

STUTTGART, Germany I March 17, 2017 I Sales of branded originator biologics in 2016 continued to reach a record high of US$ 163 bln, a plus of 5.8% compared with the previous year. Growth drivers were therapeutic antibodies fortreatment of

Posted January 25, 2017

Oncolytic Viruses: a still undervalued technology with strong growth perspectives

STUTTGART, Germany I January 25, 2017 I The acquisition of oncolytic virus company BioVex by Amgen in late 2011 for up to US$ 1 bln has been a game changer for the field of oncolytic viruses, now recognized as a

Posted August 10, 2016

Beyond anti-CD19 CAR T-Cells: the future of CAR T-cells depends on the convergence of technologies

STUTTGART, Germany I August 10, 2016 I Immunotherapy of B-cell malignancies with specifically targeted autologous T-cells most probably will see the first adoptive cell therapy products approved in the year 2017. Novartis, Kite Pharma and Juno Therapeutics are in a